Plague

The Plague is a deadly disease that affects both humans and animals. It progresses at a fast rate, killing untreated creatures within days from discovery. It can be caught in any biome.

Overview

Plague is a disease that is rapidly fatal for humans. If left untreated, it kills in 1.5 days, but rest and good treatment can slow the disease to the point where it takes 3 days to kill. It takes around 2.121 days to develop immunity to the plague - assuming the affected colonist is rested in an ordinary bed for the whole time, has normal blood filtration, is well-fed, and under the age of 40. Animals are more resistant to the disease, but still need treatment.

A skilled doctor, medicine, and healthy Blood Filtration organs (kidneys and liver) are critical to survival. The bonus immunity gain speed could mean the difference between life and death.

Prevention

Penoxycyline prevents colonists from falling sick to the Plague, but does nothing to stop an infection already in progress.

Stages

Extreme (Initial) and Extreme (Advanced) both display as just "Extreme" ingame, but have different symptoms.

Minor

• +20% Pain
• −5% Consciousness
• −5% Manipulation

Major

• +35% Pain
• −20% Consciousness
• −20% Manipulation

Extreme (Initial)

• +60% Pain
• −30% Consciousness
• −30% Manipulation

Extreme (Advanced)

• +85% Pain
• −30% Consciousness
• −30% Manipulation
• −15% Breathing
• Death at 1 severity.

Progression

Stages

This disease is detected immediately. Severity goes up over time, and is slowed by treatment until immunity is reached.

• Minor - Severity: 0 - 0.59
• Major - Severity: 0.6 - 0.79
• Extreme (Initial) - Severity: 0.8 - 0.9
• Extreme (Advanced) - Severity 0.91 - 0.99
• Death - Severity 1

Humans

• When not immune, severity increases by 0.666 per day.
• When immune, severity decreases by 0.333 per day.
• Immunity increases by 0.5224 per day when sick.
• Treatment slows progression by a maximum of 0.3628 per day.
  • This means the disease will progress by 0.3032 per day at 100% tend quality.

Animals

Animals can face the same disease, but their immunity increases faster, and treatment slows progression more.

• When not immune, severity increases by 0.666 per day.
• When immune, severity decreases by 0.333 per day.
• Immunity increases by 0.6092 per day when sick.
• Treatment slows progression by a maximum of 0.4254 per day.
  • This means the disease will progress by 0.2406 per day at 100% treatment.

Treatment

Ensure the afflicted pawns get as much bed rest as possible by prioritizing 'Rest until Healed', and get them the best medical treatment available. For humans, treatment is administered once every 15 hours. For animals, treatment is administered every 48 hours (2 days).

On a constantly resting, well-fed pawn with 100% Immunity Gain Speed, you'll need at least 15% average treatment quality to slow the plague's progression down sufficiently so that it doesn't kill the victim.

Vulnerable

For those with a base immunity gain rate of 47% or less, it will be very difficult to survive plague. This includes people well past their Life Expectancy, and/or people with severe kidney and liver damage. Even with 100% treatment quality for all treatments and rest in a hospital bed with a vitals monitor connected, they will die without extra care. To save the colonist, you can do one or more of the following:

• Tend with glitterworld medicine
• Administer healer mech serum - instantly treats the disease
• Administer luciferium
• Perform an organ transplant for pawns with damage to their liver or kidneys.
• Install detoxifier kidneys. these improve immunity gain speed by 2.5% each. Prioritize installing detoxifier kidneys on already damaged kidneys.
• Install up to two immunoenhancers for 8% per enhancer installed. Note that these require a kidney to be present for them to be installed into, so a transplant might be required if they are missing. Damaged kidneys are sufficient however.
• Use the medic cycle of a Biosculpter pod.
• Use the preach health ability on the effected person
• Use the medical specialist's immunity drive
• Place the patient in a cryptosleep casket until you have one of the above.