Yayo

Yayo is a drug of 1% addiction rate that can be produced at a drug lab with 8 psychoid leaves after researching Psychite refining. Consumption provides +80% to recreation and will generate the Feeling pumped! Let's do this! thought which has a +35 mood effect and affects the body with:

Moving: +15%
Improves joy 80%
Suppresses pain ×50%
Reduces need for rest by 66%

Excessive consumption of yayo within a short timespan, or consumption in combination with other hard drugs may result in a drug overdose. Furthermore, each dose has an unavoidable 1.0% chance of instantly causing a major overdose, regardless of previous drug consumption.

Those with visible tolerance to psychite will develop chemical damage in the kidneys in a mean time of 120 days.

It is also used in the crafting of go-juice.

Crafting

Yayo can be manufactured at a drug lab for 8 psychoid leaves. Its synthesis speed is dependent on the Intellectual skill.

Withdrawal symptoms

Like Flake and Psychite tea, Yayo can cause psychite addiction. Withdrawal lasts for 30 days and causes the following symptoms:

Mood: -35
Consciousness: -20%
Moving: -20%
Manipulation: -20%
Rest Fall Rate: +30%
Hard drug binges (mtb of 40 days)
Psychotic wandering (mtb of 10 days)

Analysis

Yayo is one of three drugs that can be produced from psychoid leaves, the others being flake and psychite tea. Yayo can also be further refined into go-juice with the addition of 2 neutroamine.

Drug

Drug	Mood buff	Moving	Pain	Tiredness	Consciousness	Sight	Global working speed
Yayo	+35	+15%	×50%	×33%	-	-	-
Flake	+35	-	×50%	×33%	-	-	-
Go juice	+5	+50%	×10%	-	+20%	+35%	-
Wake-up	-	+10%	-	×80%	+10%	-	+50%

For use as a mood control drug, yayo is far preferable to flake, with stronger effects and only one fifth as addictive (1% vs 5% addictiveness). Psychite tea is considerably weaker, but it is much less addictive than either of the other two and, unlike them, has a safe usage interval. It is thus a significantly safer option than either. This makes tea far more useful for regular use, while yayo is more appropriate for mood emergencies. Though there is no minimum tolerance to get addicted to Yayo, it still contributes to tolerance to Psychite tea.

Trade

On the market, yayo is worth 50% more silver than flake, with a 20% increase in the Work To Make and a 100% increase in ingredient cost. The most economical option depends on which is the greater bottleneck: converting the leaves to the drug, or producing the leaves in the first place.

If converting the leaves into drugs is the bottleneck then there are two options. The psychoid leaves could be turned into yayo, however converting as much as possible to flake and then selling the remaining psychoid leaves themselves is even more efficient. For example, a pawn requires 35,000 ticks (9.72 mins) of work and 800 psychoid leaves to synthesize 100 yayo worth 2100. With the same amount of work, a pawn could craft 140 flake worth 1960 and consume 560 of the 800 psychoid leaves. The remaining 240 psychoid leaves are worth 456 for a total of 2416. This is not without its downsides however - fewer traders accept psychoid leaves than accept drugs and without refrigeration, the leaves will eventually rot away. Thus, if the player is likely to caravan to a settlement or receive a relevant trader before they rot entirely away, or can accommodate the refrigeration of leaves long term, converting to flake and selling the remainder of leaves is ideal. If they cannot, converting to yayo for storage may be necessary.

If psychoid leaf production is the bottleneck and there is insufficient leaf supply to fully occupy your drug synthesizers' time, producing flake is the optimum as it produces 33% more silver per leaf at the cost of 7% more work per silver.

If caravan weight is a limiting factor, yayo is worth more proportional to mass, however the low weight of all the options means this is unlikely to be relevant as a single muffalo can carry almost 20 stacks of flake worth over 20,000 silver.

Note that the third possible product for psychoid leaves, psychite tea, is economically inferior to both yayo and flake. Its primary advantage instead lies in ease of use by colonists. It is produced at a campfire or stove with the Cooking skill and requires only the Psychoid Brewing research, and thus may be a more accessible in the early game.

Trivia

Yayo is slang for Cocaine in Spanish derived from Santiago Luis Polanco Rodriguez but it's more commonly known from the quote "Chichi, get the Yayo" from Scarface (1983).[1]