Difference between revisions of "Sanguophages"

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{{Biotech}}
 
{{Biotech}}
[[File:Sanguophage.png|frameless|right]]
 
 
{{Spoiler}}
 
{{Spoiler}}
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{{Infobox main|xenotype
 +
| name = Sanguophage
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| image = Sanguophage.png
 +
| description = Sanguophages are a type of archotech-enhanced xenohuman. Powered by archites, their abilities go far beyond normal genetic enhancements. They are mentally adept and preternaturally beautiful. In combat, they can launch deadly spines and heal injured friends. They don't age or die naturally and never suffer from disease or poison. A sanguophage can make a new sanguophage by reimplanting their own xenogerm into a person.<br/>Sanguophages must regularly consume hemogen derived from human blood, and they must periodically deathrest for long periods. They're easily destroyed by fire, and slowed down by UV light.<br/>The first sanguophage appeared thousands of years ago when the lord-explorer Varan-Dur sought to control a hyperintelligent archotech and found himself transformed by it instead. Every sanguophage is descended from him. Since then, sanguophages have often been hunted because of their destabilizing power and their need for blood. Since they can pass for baseliners, many live in hiding among typical humans.<br/>Their numbers are unknown. Some think they are legends or rare irrelevancies. Some believe sanguophages secretly direct entire human civilizations. The stories speak of eternal lords ruling billions from slate-black space stations, or directing blood sacrifices at conferences in the underlayers of the deepest urbworlds.
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| short description = Sanguophages are ageless, deathless super-humans powered by archotech-created archites in the bloodstream. They are beautiful and extremely intelligent. They can heal any injury, and never suffer from disease or poison. In combat, they can launch deadly spines and heal injured friends. The price is that sanguophages must consume hemogen derived from human blood to survive, and they must periodically deathrest for long periods. They're easily destroyed by fire, and slowed down by UV light.
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<!-- Base Stats -->
 +
| type = Human
 +
| type2 = Xenotypes
 +
<!-- Xenotypes -->
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| can generate as combatant = true
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| generate with xenogerm replicating hediff chance = 0.5
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| xenogerm replicating duration left days range = 0.1~140
 +
| combat power factor = 2.5
 +
| display priority = -1000
 +
| factionless generation weight = 0
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| double xenotype chances = (Pigskin, 0.02), (Impid, 0.02), (Yttakin, 0.02), (Neanderthal, 0.02), (Waster, 0.02), (Dirtmole, 0.02)
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| genes = Hemogenic, Hemogen drain, Bloodfeeder, Coagulate, Gene implanter, Longjump legs, Ageless, Deathless, Deathrest, Piercing spine, Psy-sensitive, Low sleep, Attractive, Fast runner, Strong melee damage, Dark vision, TotalHealing, Perfect immunity, Non-senescent, Tox immunity, Superfast wound healing, Strong Melee, Strong Social, Strong Intellectual, Mild UV sensitivity, Tinderskin, Pyrophobia, Archite metabolism, Aggressive, Robust
 +
<!-- Technical -->
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| defName = Sanguophage
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| label = sanguophage
 +
| iconPath = UI/Icons/Xenotypes/Sanguophage
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| soundDefOnImplant = PawnBecameSanguophage
 +
}}
 
'''Sanguophages''' are an exceptionally rare and powerful [[Xenotypes|xenotype]] with a deathly intolerance to heat and sunlight. They use their superhuman powers to satiate their genetic need for [[hemogen|human blood]].
 
'''Sanguophages''' are an exceptionally rare and powerful [[Xenotypes|xenotype]] with a deathly intolerance to heat and sunlight. They use their superhuman powers to satiate their genetic need for [[hemogen|human blood]].
  
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Access to Low Sleep means that, even when considering deathrest, a sanguophage will have more hours of work every day. The archite genes provide eternal youth and health, and cure scars akin to [[luciferium]]. Fast walker and Robust are useful to just about any colonist. Finally, their hemogen abilities are all useful in their own way.
 
Access to Low Sleep means that, even when considering deathrest, a sanguophage will have more hours of work every day. The archite genes provide eternal youth and health, and cure scars akin to [[luciferium]]. Fast walker and Robust are useful to just about any colonist. Finally, their hemogen abilities are all useful in their own way.
 +
 +
Because of their Non-Senecent and Scarless genes they also end up being the most ideal target for [[Psychic ritual]]s{{AnomalyIcon}} with very little penalty from chronophagy{{Check Tag|Philophagy?|apart from the obvious skill loss its not stated if that ritual causes brain damage on its page}} other then a {{--|18}} Psychic Ritual Target thought {{Check Tag|Thought Template}} and dark psychic shock. Psychophagy can also be used if the sanguophage's psychic sensitivity is unwanted albeit preventing any further use for future rituals.
  
 
However, being a blood drinker does come with costs - a need for [[hemogen]] and a need for [[deathrest]]. While they are not deal-breakers, you should consider them whenever playing with a sanguophage. These are detailed below.  
 
However, being a blood drinker does come with costs - a need for [[hemogen]] and a need for [[deathrest]]. While they are not deal-breakers, you should consider them whenever playing with a sanguophage. These are detailed below.  
  
 
----
 
----
===Sanguophage needs===
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=== Sanguophage needs ===
*'''Hemogen'''
+
==== Hemogen ====
 
Sanguophages can store 100 hemogen, which can be increased by deathresting with attached [[hemopump]]s. A sanguophage consumes 10 of their stored hemogen per day, equivalent to a bloodfeed every 2 days. Hemogen reaching 0 is not fatal, but will inflict a gradually increasing penalty that eventually reaches {{Bad|x50%}} [[Consciousness]], {{++|15%}} [[pain]] and a {{--|20}} [[mood]]let. Hemogen is also required, and consumed by, the Longjump, Piercing spine, and Coagulate abilities.
 
Sanguophages can store 100 hemogen, which can be increased by deathresting with attached [[hemopump]]s. A sanguophage consumes 10 of their stored hemogen per day, equivalent to a bloodfeed every 2 days. Hemogen reaching 0 is not fatal, but will inflict a gradually increasing penalty that eventually reaches {{Bad|x50%}} [[Consciousness]], {{++|15%}} [[pain]] and a {{--|20}} [[mood]]let. Hemogen is also required, and consumed by, the Longjump, Piercing spine, and Coagulate abilities.
  
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[[Prisoner]]s are preferred as hemogen sources over colonists because the [[blood loss]] will reduce the ability to work for a short time. The mood impact of bloodfeeding is also less important on prisoners. You can give prisoners the [[Genes#Dead calm|Dead calm]] gene to make sure they don't escape while still remaining able to feed themselves from [[nutrient paste dispenser]]s or meals left in their prison. Alternatively, the [[Peg leg#Analysis|leg treatment]] will also prevent escapes and reduce their [[Market Value]], but they will need to be manually fed by colonists or [[paramedic]] mechanoids. You can also give them negative genes like [[Genes#Very unattractive|Very unattractive]] to reduce food upkeep.
 
[[Prisoner]]s are preferred as hemogen sources over colonists because the [[blood loss]] will reduce the ability to work for a short time. The mood impact of bloodfeeding is also less important on prisoners. You can give prisoners the [[Genes#Dead calm|Dead calm]] gene to make sure they don't escape while still remaining able to feed themselves from [[nutrient paste dispenser]]s or meals left in their prison. Alternatively, the [[Peg leg#Analysis|leg treatment]] will also prevent escapes and reduce their [[Market Value]], but they will need to be manually fed by colonists or [[paramedic]] mechanoids. You can also give them negative genes like [[Genes#Very unattractive|Very unattractive]] to reduce food upkeep.
  
*'''Deathrest'''
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==== Deathrest ====
 
{{Main|Deathrest}}
 
{{Main|Deathrest}}
 
Sanguophages need to [[deathrest]] once every ~30 days. This will last from 4 days (regular [[bed]]) to 2.5 days ([[deathrest casket]] + 2 [[deathrest accelerator]]s). During this time, the pawn will have their needs frozen. Lacking deathrest is like lacking hemogen - it isn't fatal, but comes with major Consciousness and mood penalties.
 
Sanguophages need to [[deathrest]] once every ~30 days. This will last from 4 days (regular [[bed]]) to 2.5 days ([[deathrest casket]] + 2 [[deathrest accelerator]]s). During this time, the pawn will have their needs frozen. Lacking deathrest is like lacking hemogen - it isn't fatal, but comes with major Consciousness and mood penalties.
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Note that deathrest comes with some benefit. You can connect with [[deathrest building]]s like the [[glucosoid pump]] to improve post-deathrest condition. [[Psycast]]ers{{RoyaltyIcon}} will appreciate using [[psychofluid pump]]s to improve their psychic abilities. However, deathrest building capacity is limited. It must be increased one at a time by the expensive and somewhat rare [[deathrest capacity serum]]. Further, unlike a [[Cryptosleep casket]], deathrest does not suspend [[Addiction]], and can be used to mitigate withdrawal symptoms.
 
Note that deathrest comes with some benefit. You can connect with [[deathrest building]]s like the [[glucosoid pump]] to improve post-deathrest condition. [[Psycast]]ers{{RoyaltyIcon}} will appreciate using [[psychofluid pump]]s to improve their psychic abilities. However, deathrest building capacity is limited. It must be increased one at a time by the expensive and somewhat rare [[deathrest capacity serum]]. Further, unlike a [[Cryptosleep casket]], deathrest does not suspend [[Addiction]], and can be used to mitigate withdrawal symptoms.
  
*'''Miscellaneous'''
+
==== Miscellaneous ====
Sanguophages have Pyrophobia, which can cause Fleeing Fire [[mental break]] if near [[fire]]. This makes it more difficult when fighting fire-based enemies like the [[tesseron]] and [[diabolus]]. In addition, they are damaged more by fire. A [[firefoam pop pack]] can be handy. However, Sanguophages are not completely unable to deal with fire: when drafted, they will still beat out flames adjacent to the tile they are standing on. However, given their vulnerabiltiy to fire and the risk of the mental break leading them into danger, this should only be attempted in emergencies.
+
Sanguophages have Pyrophobia, which can cause Fleeing Fire [[mental break]] if near [[fire]]. This makes it more difficult when fighting fire-based enemies like the [[tesseron]] and [[diabolus]]. In addition, they are damaged more by fire. A [[firefoam pop pack]] can be handy. However, Sanguophages are not completely unable to deal with fire: when drafted, they will still beat out flames adjacent to the tile they are standing on. However, given their vulnerability to fire and the risk of the mental break leading them into danger, this should only be attempted in emergencies. [[Mind-numb serum]]s{{AnomalyIcon}} prevent pyrophobia breaks and have long durations - while they remain weak to fire damage itself, keeping them under control is by far more important.
  
 
Sanguophages also have minor UV sensitivity, giving {{--|6}} [[mood]] and {{Bad|x90%}} move speed during the sunlight. Ultimately, this is a minor penalty, but one worth noting. A sanguophage is slightly slower than a base human in the day, but faster at night.
 
Sanguophages also have minor UV sensitivity, giving {{--|6}} [[mood]] and {{Bad|x90%}} move speed during the sunlight. Ultimately, this is a minor penalty, but one worth noting. A sanguophage is slightly slower than a base human in the day, but faster at night.
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----
 
----
  
===Choosing a host===
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=== Choosing a host ===
Because each xenogerm implantation has a cooldown of 2 years, not all your colonists can become a sanguophage right away. There are 2 types of colonist that deserve special mention:
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{{Stub|section=1|reason=Discuss the germline gene xenotypes and how they combine with sanguo, ideally with list of final genes/Complexity/metabolism of each vanilla germline xenotype when combined with sanguophage so that players can see what a result will be.}}
 +
Because each xenogerm implantation has a cooldown of 2 years, not all your colonists can become a sanguophage right away. Captured Sanguophages cannot be forced to implant the sanguophage gene into babies despite the option being available. There are 2 types of colonist that deserve special mention:
  
* Colonists with brain damage, or colonists with [[Ailments#Chronic|chronic conditions]] like [[frail]]. These conditions are cured by the Scarless gene, and would otherwise require [[luciferium]], [[healer mech serum]], or the [[biosculpter pod]]{{IdeologyIcon}} to treat. In a similar vein, older colonists are vulnerable to disease and said chronic conditions. Being a sanguophage renders full immunity to disease and aging, and will retroactively cure any existing conditions over time.
+
* Colonists with brain damage, or colonists with [[Ailments#Chronic|chronic conditions]] like [[frail]]. These conditions are cured by the Scarless gene, and would otherwise require [[luciferium]], [[healer mech serum]], [[biosculpter pod]]{{IdeologyIcon}} or [[Chronophagy]]{{AnomalyIcon}} to treat. In a similar vein, older colonists are vulnerable to disease and said chronic conditions. Being a sanguophage renders full immunity to disease and aging, and will retroactively cure any existing conditions over time.
  
 
* Colonists who would appreciate access to the various genes. Melee fighters will gain access to many good vampire genes, like Strong melee (skill), Strong melee damage, Robust, and Longjump, as well as all the Archite genes. Any colonist will appreciate the powers of Deathless and Scarless.
 
* Colonists who would appreciate access to the various genes. Melee fighters will gain access to many good vampire genes, like Strong melee (skill), Strong melee damage, Robust, and Longjump, as well as all the Archite genes. Any colonist will appreciate the powers of Deathless and Scarless.

Latest revision as of 01:12, 16 November 2024

Sanguophage

Sanguophage

Sanguophages are a type of archotech-enhanced xenohuman. Powered by archites, their abilities go far beyond normal genetic enhancements. They are mentally adept and preternaturally beautiful. In combat, they can launch deadly spines and heal injured friends. They don't age or die naturally and never suffer from disease or poison. A sanguophage can make a new sanguophage by reimplanting their own xenogerm into a person.
Sanguophages must regularly consume hemogen derived from human blood, and they must periodically deathrest for long periods. They're easily destroyed by fire, and slowed down by UV light.
The first sanguophage appeared thousands of years ago when the lord-explorer Varan-Dur sought to control a hyperintelligent archotech and found himself transformed by it instead. Every sanguophage is descended from him. Since then, sanguophages have often been hunted because of their destabilizing power and their need for blood. Since they can pass for baseliners, many live in hiding among typical humans.
Their numbers are unknown. Some think they are legends or rare irrelevancies. Some believe sanguophages secretly direct entire human civilizations. The stories speak of eternal lords ruling billions from slate-black space stations, or directing blood sacrifices at conferences in the underlayers of the deepest urbworlds.

Base Stats

Type
HumanXenotypes
Technical
defName
Sanguophage


Sanguophages are an exceptionally rare and powerful xenotype with a deathly intolerance to heat and sunlight. They use their superhuman powers to satiate their genetic need for human blood.

Lore[edit]

"The first sanguophage appeared thousands of years ago when the lord-explorer Varan-Dur sought to control a hyperintelligent archotech and found himself transformed by it instead. Every sanguophage is descended from him. Since then, sanguophages have often been hunted because of their destabilizing power and their need for blood. Since they can pass for baseliners, many live in hiding among typical humans.
Their numbers are unknown. Some think they are legends or rare irrelevancies. Some believe sanguophages secretly direct entire human civilizations. The stories speak of eternal lords ruling billions from slate-black space stations, or directing blood sacrifices at conferences in the underlayers of the deepest urbworlds."

— Biotech preview #4: Xenotypes, world factions, and the dark blood-drinkers

Summary[edit]

Sanguophages are a mysterious but powerful group of xenohumans. They have no distinguishing looks from other xenohumans, so they blend in at first glance. Once selected, their differences are immediately apparent, from their hemogen and deathrest trackers at the bottom of the screen, to their unique abilities and immense genetic differences.

Genes[edit]

Sanguophages have a gene complexity of 57Complexity complexity and an equivalent xenogerm contains 8Archite capsule archite capsules. With a 0Metabolic efficiency metabolic efficiency, they have a hunger rate of ×100%. Note however that sanguophage genes can disable a pawn's native germline genes (e.g. Fast Runner will negate a neanderthal's Slow Runner), which can change their metabolism.

All sanguophages have these xenogenes:

Archite:

Gene implanter
Gene implanter
Ageless
Ageless
Archite metabolism
Archite metabolism
Deathless
Deathless
Non-senescent
Non-senescent
Perfect immunity
Perfect immunity
Scarless
Scarless
Gene implanter Ageless Archite metabolism Deathless Non-senescent Perfect immunity Scarless

Hemogenic:

Bloodfeeder
Bloodfeeder
Coagulate
Coagulate
Longjump legs
Longjump legs
Piercing spine
Piercing spine
Hemogenic
Hemogenic
Hemogen drain
Hemogen drain
Deathrest
Deathrest
Bloodfeeder Coagulate Longjump legs Piercing spine Hemogenic Hemogen drain Deathrest

Assorted:

Superfast wound healing
Superfast wound healing
Psy-sensitive
Psy-sensitive
Fast runner
Fast runner
Tox immunity
Tox immunity
Mild UV sensitivity
Mild UV sensitivity
Tinderskin
Tinderskin
Pyrophobia
Pyrophobia
Superfast wound healing Psy-sensitive Fast runner Tox immunity Mild UV sensitivity Tinderskin Pyrophobia
Aggressive
Aggressive
Strong melee damage
Strong melee damage
Low sleep
Low sleep
Robust
Robust
Attractive
Attractive
Dark vision
Dark vision
Aggressive Strong melee damage Low sleep Robust Attractive Dark vision

Skills:

Strong melee
Strong melee
Strong social
Strong social
Strong intellectual
Strong intellectual
Strong melee Strong social Strong intellectual

Obtaining[edit]

Sanguophages can be found in several ways.

  • Sanguophage scenario : You start the game with a Sanguophage.
  • Recruitment: You capture and recruit a Sanguophage, or one joins as a wanderer.
  • Gene implant : You can force Sanguophages to use their gene implant ability on one of your pawns if they are captured or downed. Select the desired pawn to gain these abilities, and then right-click on the sanguophage and choose the "Absorb xenogerm" option. If the sanguophage's genes are currently regrowing, this will kill them.
  • Quest : You allow 2 or more Sanguophages hold a meeting at your colony. They will start the ceremony by placing a blood torch, which gives +2 mood buff to all sanguophages in its radius, and a red mist, with red eyes appearing in it, will appear for a few hours. The torch will remain once the quest is complete. One of the quest rewards will allow you to choose a pawn to be implanted with Sanguophage genes. There's also a small chance that some of those sanguophages will give you a join offer, similar to refugees.
  • Quest : You get word that a sanguophage and his thralls are about to crash, and you can signal them to land at your colony (or nearby). You are advised that if you capture the sanguophage you can force them to implant a xenogerm in one of your colonists.
  • StellarchsContent added by the Royalty DLC have a 25% chance of generating as a Sanguophage, separate from the xenotype set used by the empire itself. This means that there is the potential to order the high stellarch to implant their xenogerm into a colonist during the Royalty endgame quest.
    • Knights/Dames, Praetors, Barons/Baronesses and Count/Countesses also have a 5% chance to generate as a Sanguophage, and Duke/Duchesses and Consuls have a 15% chance.

Analysis[edit]

Becoming a sanguophage has a variety of pros and cons, that are generally worth the implantation.

Access to Low Sleep means that, even when considering deathrest, a sanguophage will have more hours of work every day. The archite genes provide eternal youth and health, and cure scars akin to luciferium. Fast walker and Robust are useful to just about any colonist. Finally, their hemogen abilities are all useful in their own way.

Because of their Non-Senecent and Scarless genes they also end up being the most ideal target for Psychic ritualsContent added by the Anomaly DLC with very little penalty from chronophagy[Philophagy?] other then a −18 Psychic Ritual Target thought [Thought Template] and dark psychic shock. Psychophagy can also be used if the sanguophage's psychic sensitivity is unwanted albeit preventing any further use for future rituals.

However, being a blood drinker does come with costs - a need for hemogen and a need for deathrest. While they are not deal-breakers, you should consider them whenever playing with a sanguophage. These are detailed below.


Sanguophage needs[edit]

Hemogen[edit]

Sanguophages can store 100 hemogen, which can be increased by deathresting with attached hemopumps. A sanguophage consumes 10 of their stored hemogen per day, equivalent to a bloodfeed every 2 days. Hemogen reaching 0 is not fatal, but will inflict a gradually increasing penalty that eventually reaches ×50% Consciousness, +15% pain and a −20 moodlet. Hemogen is also required, and consumed by, the Longjump, Piercing spine, and Coagulate abilities.

As a rough measure, each regular human can meet 1.48 sanguophages' needs for blood indefinitely, assuming no hemogenic abilities are used. Extracting hemogen packs and consuming them is exactly as efficient as blood feeding in terms of hemogen per prisoner per day. Packs require storage space and additional pawn work, but do not inflict a painful bite or a −5 moodlet, and extracting them slowly trains the medical skill. Note that the moodlet is avoided when feeding on masochists or those with the Bloodfeeders: Revered precept.Content added by the Ideology DLC

Prisoners are preferred as hemogen sources over colonists because the blood loss will reduce the ability to work for a short time. The mood impact of bloodfeeding is also less important on prisoners. You can give prisoners the Dead calm gene to make sure they don't escape while still remaining able to feed themselves from nutrient paste dispensers or meals left in their prison. Alternatively, the leg treatment will also prevent escapes and reduce their Market Value, but they will need to be manually fed by colonists or paramedic mechanoids. You can also give them negative genes like Very unattractive to reduce food upkeep.

Deathrest[edit]

Sanguophages need to deathrest once every ~30 days. This will last from 4 days (regular bed) to 2.5 days (deathrest casket + 2 deathrest accelerators). During this time, the pawn will have their needs frozen. Lacking deathrest is like lacking hemogen - it isn't fatal, but comes with major Consciousness and mood penalties.

The main cost of deathrest is that your sanguophage might be stuck sleeping whenever a raid arrives. Cassandra Classic and Phoebe Chillax both have defined cooldowns between sets of raids, but Randy Random won't give you that mercy. They can wake up at will, but this results in the Interrupted deathrest hediff, reducing their stats for 5 days.

Note that deathrest comes with some benefit. You can connect with deathrest buildings like the glucosoid pump to improve post-deathrest condition. PsycastersContent added by the Royalty DLC will appreciate using psychofluid pumps to improve their psychic abilities. However, deathrest building capacity is limited. It must be increased one at a time by the expensive and somewhat rare deathrest capacity serum. Further, unlike a Cryptosleep casket, deathrest does not suspend Addiction, and can be used to mitigate withdrawal symptoms.

Miscellaneous[edit]

Sanguophages have Pyrophobia, which can cause Fleeing Fire mental break if near fire. This makes it more difficult when fighting fire-based enemies like the tesseron and diabolus. In addition, they are damaged more by fire. A firefoam pop pack can be handy. However, Sanguophages are not completely unable to deal with fire: when drafted, they will still beat out flames adjacent to the tile they are standing on. However, given their vulnerability to fire and the risk of the mental break leading them into danger, this should only be attempted in emergencies. Mind-numb serumsContent added by the Anomaly DLC prevent pyrophobia breaks and have long durations - while they remain weak to fire damage itself, keeping them under control is by far more important.

Sanguophages also have minor UV sensitivity, giving −6 mood and ×90% move speed during the sunlight. Ultimately, this is a minor penalty, but one worth noting. A sanguophage is slightly slower than a base human in the day, but faster at night.


Choosing a host[edit]

Because each xenogerm implantation has a cooldown of 2 years, not all your colonists can become a sanguophage right away. Captured Sanguophages cannot be forced to implant the sanguophage gene into babies despite the option being available. There are 2 types of colonist that deserve special mention:

  • Colonists with brain damage, or colonists with chronic conditions like frail. These conditions are cured by the Scarless gene, and would otherwise require luciferium, healer mech serum, biosculpter podContent added by the Ideology DLC or ChronophagyContent added by the Anomaly DLC to treat. In a similar vein, older colonists are vulnerable to disease and said chronic conditions. Being a sanguophage renders full immunity to disease and aging, and will retroactively cure any existing conditions over time.
  • Colonists who would appreciate access to the various genes. Melee fighters will gain access to many good vampire genes, like Strong melee (skill), Strong melee damage, Robust, and Longjump, as well as all the Archite genes. Any colonist will appreciate the powers of Deathless and Scarless.
Their pyrophobia will negate the Pyromaniac trait. Pawns with Transhumanist ideologiesContent added by the Ideology DLC can also go without mandatory age reversals.

Remember that Sanguophage implantation replaces all xenogenes. Your genies, hussars, and highmates will lose all of their respective genes. Any xenogerms you've implanted will be replaced completely. In addition, placing any xenogerm will erase all the Sanguophage genes. Don't give them Great Melee thinking it'll just improve your sanguophage's melee skill, it'll also remove their archite genes and need for blood.

Version history[edit]

  • 1.4.3531 - Fix: AI sanguophages can use longjump without any remaining hemogen.
  • 1.4.3534 - Fix: Error on drafting pawn with hemogenic ability gene with no hemogen gene.